# Introduction to PIC-SURE

Patient Information Commons: Standard Unification of Research Elements (PIC-SURE) is a platform that integrates clinical and genomic datasets from multiple data sources to allow researchers to search for data, apply filters, and explore data from selected cohorts of patients.

PIC-SURE can be explored on the demo site here: [https://nhanes.hms.harvard.edu/ ](https://nhanes.hms.harvard.edu/)

This site uses publicly available data to demonstrate key PIC-SURE functionality:

* National Health and Nutrition Examination Survey (NHANES)
  * The National Health and Nutrition Examination Survey (NHANES) collects data about the health of adults and children in the United States. Learn more at [the CDC's NHANES website here](https://www.cdc.gov/nchs/nhanes/about/index.html).&#x20;
* The 1000 Genomes Project
  * The 1000 Genomes Project created a catalogue of common human genetic variation, using openly consented samples from people who declared themselves to be healthy. Learn more at the [International Genome Sample Resource's 1000 Genomes website here](https://www.internationalgenome.org/).&#x20;
* Synthea
  * Synthea is an open-source, synthetic patient generator that models the medical history of synthetic patients. Learn more about [the Synthea dataset at their website here](https://synthetichealth.github.io/synthea/).&#x20;


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# Agent Instructions: Querying This Documentation

If you need additional information that is not directly available in this page, you can query the documentation dynamically by asking a question.

Perform an HTTP GET request on the current page URL with the `ask` query parameter:

```
GET https://pic-sure.gitbook.io/pic-sure/getting-started/introduction-to-pic-sure.md?ask=<question>
```

The question should be specific, self-contained, and written in natural language.
The response will contain a direct answer to the question and relevant excerpts and sources from the documentation.

Use this mechanism when the answer is not explicitly present in the current page, you need clarification or additional context, or you want to retrieve related documentation sections.
